SIRP alpha Antibody

CAT: 0667-KC-1076-01Size: 50 μLDry Ice: NoHazardous: No

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CAT#:0667-KC-1076-01Size:50 μL

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Product Name Alternative

Tyrosine-protein phosphatase non-receptor type substrate 1, SHP substrate 1, SHPS-1, Brain Ig-like molecule with tyrosine-based activation motifs, Bit, CD172 antigen-like family member A, Inhibitory receptor SHPS-1, Macrophage fusion receptor, MyD-1 antigen, Signal-regulatory protein alpha-1, Sirp-alpha-1, Signal-regulatory protein alpha-2, Sirp-alpha-2, Signal-regulatory protein alpha-3, Sirp-alpha-3, p84, CD antigen CD172a

Gene Name

SIRPA

Gene ID

140885

UniProt

P78324

Antigen Species

Human

Reactivity

Human

Cross Reactivity

Not tested

Immunogen

Recombinant human SIRPA

Target Antigen

CD172a

Target

PP-817

Partner Proteins

Tyrosine-protein phosphatase non-receptor type substrate 1; SHP substrate 1; SHPS-1; Brain Ig-like molecule with tyrosine-based activation motifs; Bit; CD172 antigen-like family member A; Inhibitory receptor SHPS-1; Macrophage fusion receptor; MyD-1 antigen; Signal-regulatory protein alpha-1; Sirp-alpha-1; Signal-regulatory protein alpha-2; Sirp-alpha-2; Signal-regulatory protein alpha-3; Sirp-alpha-3; p84; CD antigen CD172a

Clone

K06318_24E11

Conjugation

Unconjugated

Applications

IHC

Validation

IHC

Homology

Highest antigen sequence identity to the following orthologs: Mouse - 79%, Rat - 81%, Pig - 85%, Cynomolgus monkey - 98%

Purity

≥85%

Cores

AQGSTSSTRLHEPEKNAREITQDTNDITYADLNLPKGKKPAPQAAEPNNHTEYASIQTSPQPASEDTLTYADLDMVHLNRTPKQPAPKPEPSFSEYASVQ

Storage Temperature

Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower

Identity Mouse

79%

Recombinant Antibody

Not recombinant

IHC Dilution

1:200

Formulation

Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide

Antibody Type

Monoclonal

Gene Name Synonym

BIT; MFR; MYD1; PTPNS1; SHPS1; SIRP

Target Alternative Name

SIRP alpha

Panel Description

CD Antigen

Host or Source

Mouse

Protein Name

Signal regulatory protein alpha

WB Description

Fail (THP-1)

IHC description

Succeed

IP description

Fail (THP-1)

Shipping Temperature

Shipped at ambient temperature or with ice packs.

Isotype

IgG1

UniProtKB · P78324

Tyrosine-protein phosphatase non-receptor type substrate 1

SHPS1_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P78324
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: SIRPA
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: SHP substrate 1, SHPS-1
EC number: —
Processing: Precursor
Secondary accessions: A2A2E1, A8K411, B2R6C3, O00683, O43799, Q8N517, Q8TAL8, Q9H0Z2, Q9UDX2, Q9UIJ6, Q9Y4U9

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

PTM

Disulfide bondGlycoproteinPhosphoprotein

Domain

Immunoglobulin domainRepeatSH3-bindingSignalTransmembraneTransmembrane helix

Cellular component

Membrane

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