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Alpha Fodrin Antibody

CAT: 0667-KC-30505-01Size: 50 μLDry Ice: NoHazardous: No
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CAT#:0667-KC-30505-01Size:50 μL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Product Name Alternative
Spectrin alpha chain, non-erythrocytic 1, Alpha-II spectrin, Fodrin alpha chain, Spectrin, non-erythroid alpha subunit
Gene Name
SPTAN1
Gene ID
6709
UniProt
Q13813
Antigen Species
Human
Reactivity
Human, Mouse
Cross Reactivity
Not tested
Immunogen
Recombinant human SPTAN1
Target
PP-5039
Partner Proteins
Spectrin alpha chain; non-erythrocytic 1; Alpha-II spectrin; Fodrin alpha chain; Spectrin; non-erythroid alpha subunit
Clone
K92088_4D3
Conjugation
Unconjugated
Applications
Top_IHC&Top_WB
Validation
Top_IHC&Top_WB
Homology
Highest antigen sequence identity to the following orthologs: Mouse - 99%, Rat - 99%, Pig - 98%, Cynomolgus monkey - 100%
Purity
≥85%
Cores
TAEDIQERRQQVLDRYHRFKELSTLRRQKLEDSYRFQFFQRDAEELEKWIQEKLQIASDENYKDPTNLQGKLQKHQAFEAEVQANSGAIVKLDETGNLMISEGHFASETIRTRLMELHRQWELLLEKMREKGIKLLQAQKLVQYLRECEDVMDWINDKEAIVTSEELGQDLEHVEVLQKKFEEFQTDMAAHEERVNEVNQFAAKLIQEQHPEEELIKTKQDEVNAAWQRLKGLALQRQGK
Storage Temperature
Avoid repeated freeze-thaw cycles. Upon receipt, * 1 month when stored at 2 to 8 °C * 12 months when aliquoted and stored at -20 °C or lower
Identity Mouse
99%
Recombinant Antibody
Not recombinant
IHC Dilution
1:2000
WB Dilution
1:1000
Formulation
Phosphate-buffered saline (PBS) with 50% glycerol, 0.5% BSA and 0.09% sodium azide
Antibody Type
Monoclonal
Gene Name Synonym
NEAS; SPTA2
Target Alternative Name
Alpha Fodrin
Panel Description
Autoimmune Disease, Neuroscience Biomarkers
Host or Source
Mouse
Protein Name
Spectrin alpha, non-erythrocytic 1
WB Description
Succeed
IHC description
Succeed
IP description
Fail (Mouse Brain)
Shipping Temperature
Shipped at ambient temperature or with ice packs.
Isotype
IgG1

UniProtKB · Q13813

Spectrin alpha chain, non-erythrocytic 1

SPTN1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q13813
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
SPTAN1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
—
Processing
—
Secondary accessions
Q13186, Q15324, Q16606, Q59EF1, Q5VXV5, Q5VXV6, Q7Z6M5, Q9P0V0
Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

PTM

AcetylationPhosphoprotein

Molecular function

Actin cappingActin-bindingCalmodulin-binding

Coding sequence diversity

Alternative splicing

Ligand

CalciumMetal-binding

Cellular component

CytoplasmCytoskeleton

Disease

Disease variantEpilepsyHereditary spastic paraplegiaIntellectual disabilityNeurodegenerationNeuropathy

Domain

RepeatSH3 domain