Alk Protein, Active

• Description:

  Alk Protein, Active_x000D_ Catalog number: B2023626_x000D_ Lot number: Batch Dependent_x000D_ Expiration Date: Batch dependent_x000D_ Amount: 10 ug_x000D_ Molecular Weight or Concentration: 63.8 kDa_x000D_ Supplied as: Resin_x000D_ Applications: a molecular tool for various biochemical applications_x000D_ Storage: -70°C_x000D_ Keywords: Anaplastic lymphoma kinase_x000D_ Grade: Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity >18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ References:_x000D_ 1. You L., Wang Z., Li H., & Shou J. (2015). The role of STAT3 in autophagy. *Autophagy*, 11(5), 729-39._x000D_ _x000D_ 2. Skoulidis F. & Heymach J.V. (2019). Co-occurring genomic alterations in non-small-cell lung cancer biology and therapy. *Nat Rev Cancer*, 19(9), 495-509._x000D_ _x000D_ 3. Tulpule A., Guan J., Neel D.S., Allegakoen H.R. (2001). Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules. *Cell*, 184(10), 2649-2664._x000D_ _x000D_ 4. Chen D, Zhao M, & Mundy GR.. (2004). Bone morphogenetic proteins. *Growth Factors*, 22(4), 233-41._x000D_ _x000D_ 5. Rybarczyk-Kasiuchnicz A, Ramlau R, & Stencel K.. (2021). Treatment of Brain Metastases of Non-Small Cell Lung Carcinoma. *Int J Mol Sci*, 106(4), 473-481._x000D_ _x000D_ 6. Xu Z., Pan Z., Jin Y., & Gao Z. (2024). Inhibition of PRKAA/AMPK (Ser485/491) phosphorylation by crizotinib induces cardiotoxicity via perturbing autophagosome-lysosome fusion. *Autophagy*, 20(2), 416-436._x000D_ _x000D_ 7. Reshetnyak A.V., Rossi P., Myasnikov A.G., Sowaileh M. (2021). Mechanism for the activation of the anaplastic lymphoma kinase receptor. *Nature*, 600(7887), 153-157._x000D_ _x000D_ 8. Rikova K., Guo A., Zeng Q., & Possemato A. (2007). Global survey of phosphotyrosine signaling identifies oncogenic kinases in lung cancer. *Cell*, 131(6), 1190-203._x000D_ _x000D_ 9. Chuang T.P., Lai W.Y., Gabre J.L., & Lind D.E. (2023). ALK fusion NSCLC oncogenes promote survival and inhibit NK cell responses via SERPINB4 expression. *Proc Natl Acad Sci U S A*, 120(8), e2216479120._x000D_ _x000D_ 10. Li T., Stayrook S.E., Tsutsui Y., & Zhang J. (2021). Structural basis for ligand reception by anaplastic lymphoma kinase. *Nature*, 600(7887), 148-152._x000D_ https://pubmed.ncbi.nlm.nih.gov/?term=Alk Protein, Active_x000D_ _x000D_ Products Related to Alk Protein, Active can be found at Proteins

• Short Description:

  Catalog Number: B2023626 (10 ug)

• Weight:

  0.15

• Length:

  2

• Width:

  0.5

• Height:

  0.5