SAH-SOS1A

CAT: 1410-M30796-01Size: 100 mgDry Ice: NoHazardous: No
CAT#:1410-M30796-01Size:100 mg
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Description
KRas/son of sevenless 1 (SOS1) interaction inhibitor. Binds within nucleotide binding pocket of KRas (Kd values are 106 - 176 nM for wild type KRas and various KRas mutants) . Inhibits nucleotide binding to KRas in a concentration dependent manner. Displays cytotoxicity in KRas-driven cancer cell lines and inhibits downstream ERK-MAPK signaling. Cell permeable.
CAS Number
1652561-87-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
2187.53
Molecular Formula
C100H159N27O28
Notes
Research use only, not for human use.
Receptor
——

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