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TAT-cyclo-CLLFVY

CAT: 1410-M30710Size: 1 EachDry Ice: NoHazardous: No
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CAT#:1410-M30710Size:1 Each
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Description
Selective HIF-1 dimerization inhibitor. Blocks protein-protein interaction of recombinant HIF-1α, but not HIF-2α, with HIF-1β (IC50 = 1.3 μM) . Inhibits hypoxia-induced HIF-1 activity, and decreases VEGF and CAIX expression in osteosarcoma and breast cancer cells in vitro. Also reduces tubularization of hypoxic HUVECs.
CAS Number
1446322-66-2
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
2559.1
Molecular Formula
C111H188N42O24S2
Notes
Research use only, not for human use.
Receptor
——

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