Products for Research Use Only

PY-60

CAT: 1410-M37636-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1410-M37636-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
PY-60 can effectively activate YAP transcriptional activity against annexin A2 (ANXA2) (Kd value of 1.4 µM) . PY-60 activates a pro-proliferative, YAP-dependent transcriptional program in adult animals that are able to remodel the epidermis through proliferation.
CAS Number
2765218-56-0
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
313.37
Molecular Formula
C16H15N3O2S
Notes
Research use only, not for human use.
Receptor
YAP | Annexin A

Chemical Information

5-Phenyl-N-(3-(thiazol-2-yl)propyl)isoxazole-3-carboxamide
CAS Number2765218-56-0
PubChem CID155387479
IUPAC Name5-phenyl-N-[3-(1,3-thiazol-2-yl)propyl]-1,2-oxazole-3-carboxamide
Molecular FormulaC16H15N3O2S
Molecular Weight313.4
XLogP3
Topological Polar Surface Area96.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Heavy Atom Count22
Formal Charge0
Complexity363
SMILES
C1=CC=C(C=C1)C2=CC(=NO2)C(=O)NCCCC3=NC=CS3
InChI
InChI=1S/C16H15N3O2S/c20-16(18-8-4-7-15-17-9-10-22-15)13-11-14(21-19-13)12-5-2-1-3-6-12/h1-3,5-6,9-11H,4,7-8H2,(H,18,20)
InChIKey
UFASECSYKSMYET-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-Phenyl-N-(3-(thiazol-2-yl)propyl)isoxazole-3-carboxamide
CAS: 2765218-56-0
CID: 155387479
Formula: C16H15N3O2S
MW: 313.4
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight313.4
XLogP33
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count5
Rotatable Bond Count6
Exact Mass313.08849790
Monoisotopic Mass313.08849790
Topological Polar Surface Area96.3 Ų
Heavy Atom Count22
Formal Charge0
Complexity363
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes