BML-278

• Description :

  BML-278 is a SIRT1 activator with an EC150 of 1 μM. It increases H3K9 methylation and inhibits H3K9 acetylation in parental and maternal prokaryotes, improving early embryonic development. BML-278 induces cell cycle arrest at the G1/S phase in primary human mesenchymal stromal cells, delaying senescence. It also reduces microtubule protein acetylation in U937 cells and increases mitochondrial density in mouse C2C12 myoblasts.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  391.46

• Molecular Formula :

  C24H25NO4

• Notes :

  Research use only, not for human use.

• Receptor :

  Sirtuin | Histone Methyltransferase

• CAS Number :

  120533-76-8