Products for Research Use Only

MK-28

CAT: 1410-M35599-05Size: 50 mgDry Ice: NoHazardous: No
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CAT#:1410-M35599-05Size:50 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
MK-28 is a selective PERK agonist that reduces toxicity and prolongs survival in a Huntington's disease model.MK-28 has a significant killing effect on MK28 gastric cancer cells.
CAS Number
864388-65-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
396.44
Molecular Formula
C24H20N4O2
Notes
Research use only, not for human use.
Receptor
PERK | Antiviral

Chemical Information

CID 135715675
CAS Number864388-65-8
PubChem CID135715675
IUPAC Name4-[(E)-[(4,6-diphenylpyrimidin-2-yl)-methylhydrazinylidene]methyl]benzene-1,2-diol
Molecular FormulaC24H20N4O2
Molecular Weight396.4
XLogP4.9
Topological Polar Surface Area81.8
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Heavy Atom Count30
Formal Charge0
Complexity521
SMILES
CN(C1=NC(=CC(=N1)C2=CC=CC=C2)C3=CC=CC=C3)/N=C/C4=CC(=C(C=C4)O)O
InChI
InChI=1S/C24H20N4O2/c1-28(25-16-17-12-13-22(29)23(30)14-17)24-26-20(18-8-4-2-5-9-18)15-21(27-24)19-10-6-3-7-11-19/h2-16,29-30H,1H3/b25-16+
InChIKey
GKOVHCFOVLXKFL-PCLIKHOPSA-N
Chemical Structure
2D Structure
2D structure of CID 135715675
CAS: 864388-65-8
CID: 135715675
Formula: C24H20N4O2
MW: 396.4
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight396.4
XLogP34.9
Hydrogen Bond Donor Count2
Hydrogen Bond Acceptor Count6
Rotatable Bond Count5
Exact Mass396.15862589
Monoisotopic Mass396.15862589
Topological Polar Surface Area81.8 Ų
Heavy Atom Count30
Formal Charge0
Complexity521
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes