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DDO-7263

CAT: 1410-M35426-02Size: 1 mL x 10 mM in DMSODry Ice: NoHazardous: No
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CAT#:1410-M35426-02Size:1 mL x 10 mM in DMSO
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
DDO-7263 is a 1,2,4-Oxadiazole derivative that upregulates Nrf2 through binding to Rpn6 to block the assembly of 26S proteasome and the subsequent degradation of ubiquitinated Nrf2. DDO-7263 is a potent Nrf2 activator that activates the Nrf2-ARE signaling pathway and exerts anti-inflammatory activity .
CAS Number
2254004-96-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
273.24
Molecular Formula
C14H9F2N3O
Notes
Research use only, not for human use.
Receptor
Nrf2

Chemical Information

5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole
CAS Number2254004-96-9
PubChem CID145989809
IUPAC Name5-(3,4-difluorophenyl)-3-(6-methyl-3-pyridinyl)-1,2,4-oxadiazole
Molecular FormulaC14H9F2N3O
Molecular Weight273.24
XLogP3
Topological Polar Surface Area51.8
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Heavy Atom Count20
Formal Charge0
Complexity334
SMILES
CC1=NC=C(C=C1)C2=NOC(=N2)C3=CC(=C(C=C3)F)F
InChI
InChI=1S/C14H9F2N3O/c1-8-2-3-10(7-17-8)13-18-14(20-19-13)9-4-5-11(15)12(16)6-9/h2-7H,1H3
InChIKey
HITVBBDLWZDVIV-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of 5-(3,4-Difluorophenyl)-3-(6-methylpyridin-3-yl)-1,2,4-oxadiazole
CAS: 2254004-96-9
CID: 145989809
Formula: C14H9F2N3O
MW: 273.24
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight273.24
XLogP33
Hydrogen Bond Donor Count0
Hydrogen Bond Acceptor Count6
Rotatable Bond Count2
Exact Mass273.07136824
Monoisotopic Mass273.07136824
Topological Polar Surface Area51.8 Ų
Heavy Atom Count20
Formal Charge0
Complexity334
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
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CatalogName
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HY-149863DDO-8926
T207588-01DDO-6691
T205089-01DDO-3055
T62283-01DDO-02005
T9202-01DDO-5936
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