GA-017

• Description:

  GA-017 is a potent, selective inhibitor of LATS1 and LATS2 (large tumor suppressor kinase 1/2), exhibiting IC50 values of 4.10 and 3.92 nM, respectively. This compound simultaneously acts as an activator of cell proliferation by promoting YAP/TAZ activation and their nuclear translocation. Additionally, GA-017 enhances cell growth in 3D culture conditions and augments the ex vivo formation of mouse intestinal organoids .

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  343.38

• Molecular Formula:

  C18H21N3O4

• Notes:

  Research use only, not for human use.

• Receptor:

  Others

• CAS Number:

  2351906-74-4