(±) 8 (9) -EpETE

• Description:

  Eicosapentaenoic acid is converted to epoxyeicosatetraenoic acids (EpETEs) by several cytochrome P450 isoforms. The major product of this epoxygenase pathway, (±) 17 (18) -EpETE , relaxes vascular and airway smooth muscle by activating large conductance Ca2+-activated K+ (BKCa) channels by directly interacting with BKα channel subunits. (±) 8 (9) -EpETE is an epoxygenase pathway product produced from EPA by CYP450 both in vitro and in vivo. The biological actions and physiological effects of this epoxide remain to be determined.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  318.457

• Molecular Formula:

  C20H30O3

• Notes:

  Research use only, not for human use.

• Receptor:

  Others

• CAS Number:

  851378-93-3