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Tyrphostin 8

CAT: 1410-M34726-01Size: 1 EachDry Ice: NoHazardous: No
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Description
Tyrphostin 8 (4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein serine/threonine calmodulin phosphatases (IC50=21 μM), enhances transferrin receptor-mediated transcytosis in Caco-2 cells, and increases the hypoglycemic effect of oral insulin-transferrin. hypoglycemic effect.
CAS Number
3785-90-8
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
170.17
Molecular Formula
C10H6N2O
Notes
Research use only, not for human use.
Receptor
GTPase | EGFR | Phosphatase

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