Tyrphostin 8

• Description :

  Tyrphostin 8 (4-Hydroxybenzylidenemalononitrile) is a potent GTPase inhibitor that inhibits EGFR kinase with an IC50 of 560 μM.Tyrphostin 8 inhibits protein serine/threonine calmodulin phosphatases (IC50=21 μM), enhances transferrin receptor-mediated transcytosis in Caco-2 cells, and increases the hypoglycemic effect of oral insulin-transferrin. hypoglycemic effect.

• Stability :

  ≥ 2 years

• Purity :

  >98% (HPLC)

• Weight :

  170.17

• Molecular Formula :

  C10H6N2O

• Notes :

  Research use only, not for human use.

• Receptor :

  GTPase | EGFR | Phosphatase

• CAS Number :

  3785-90-8