GSK-843

• Description:

  GSK-843 (GSK'843) is a selective and potent RIP3 inhibitor with an IC50 value of 8.6 nM for the structural domain of RIP3 kinase. It has potential analgesic activity, inhibits the expression of RIP3 and NLRP3 in the SDH of CFA mice, and can be used as adjunctive therapy for treating inflammation.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  377.49

• Molecular Formula:

  C19H15N5S2

• Notes:

  Research use only, not for human use.

• Receptor:

  RIP kinase

• CAS Number:

  1601496-05-2