GSK-843

• Target :

  Apoptosis|||RIP kinase

• Related Pathways :

  NF-?B|||Apoptosis

• Purity :

  0.9918

• Bioactivity :

  GSK-843 (GSK'843) is a selective and potent RIP3 inhibitor with an IC50 value of 8.6 nM for the structural domain of RIP3 kinase. It has potential analgesic activity, inhibits the expression of RIP3 and NLRP3 in the SDH of CFA mice, and can be used as adjunctive therapy for treating inflammation.

• Smiles :

  Cc1cc(-c2cnc(N)c3c(csc23)-c2ccc3scnc3c2)n(C)n1

• Molecular Formula :

  C19H15N5S2

• Molecular Weight :

  377.49

• Shipping Conditions :

  Cool pack

• Storage Temperature :

  -20°C

• CAS Number :

  1601496-05-2