Products for Research Use Only
RegisterLogin

CS-2660

CAT: 1410-M25002-05Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M25002-05Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
CS-2660, a highly selective, orally available, well tolerated VEGFR2 inhibitor with IC50 of 40 nM, inhibits closely related tyrosine kinases such as Ret and Kit with IC50 of 180 nM and 500 nM.
CAS Number
951151-97-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
364.79
Molecular Formula
C15H17ClN6O3
Notes
Research use only, not for human use.
Receptor
Kit|Ret|VEGFR2

Chemical Information

Jnj-38158471
CAS Number951151-97-6
PubChem CID16742063
IUPAC Name1-[4-[6-amino-5-[(E)-methoxyiminomethyl]pyrimidin-4-yl]oxy-2-chlorophenyl]-3-ethylurea
Molecular FormulaC15H17ClN6O3
Molecular Weight364.79
XLogP1.8
Topological Polar Surface Area124
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Heavy Atom Count25
Formal Charge0
Complexity455
SMILES
CCNC(=O)NC1=C(C=C(C=C1)OC2=NC=NC(=C2/C=N/OC)N)Cl
InChI
InChI=1S/C15H17ClN6O3/c1-3-18-15(23)22-12-5-4-9(6-11(12)16)25-14-10(7-21-24-2)13(17)19-8-20-14/h4-8H,3H2,1-2H3,(H2,17,19,20)(H2,18,22,23)/b21-7+
InChIKey
BJHCYTJNPVGSBZ-QPSGOUHRSA-N
Chemical Structure
2D Structure
2D structure of Jnj-38158471
CAS: 951151-97-6
CID: 16742063
Formula: C15H17ClN6O3
MW: 364.79
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight364.79
XLogP31.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count7
Rotatable Bond Count6
Exact Mass364.1050661
Monoisotopic Mass364.1050661
Topological Polar Surface Area124 Ų
Heavy Atom Count25
Formal Charge0
Complexity455
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count1
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M27618-01CS 2100
M16073CS-0777
M14004-01CS-526
M23229-01CS-0047390
M12453-01CS-3150
M32869-01CS-722 Free base
M28487-01BTT-266
M21282-01266-Trimethyl-24-cycloheptadien-1-one

Alternative Products

CatalogName
MBS3614603-01CS-2660
C07154-01CS-2660 (JNJ-38158471)
NBP3-07405-100ugMouse Monoclonal Myogenin Antibody (MYOG/2660)
CSB-CL006031HU2CS
NBP3-08544HMouse Monoclonal Myogenin Antibody (MYOG/2660) [HRP]
NBP3-08544BMouse Monoclonal Myogenin Antibody (MYOG/2660) [Biotin]
NBP3-08544PEMouse Monoclonal Myogenin Antibody (MYOG/2660) [PE]
NBP3-08544APCMouse Monoclonal Myogenin Antibody (MYOG/2660) [Allophycocyanin]
034263CS, NT (CS, Citrate synthase, mitochondrial)
B5636-50CS 2100

Popular Products