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Limaprost

CAT: 1410-M22940-05Size: 50 mgDry Ice: NoHazardous: No
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CAT#:1410-M22940-05Size:50 mg
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Description
Limaprost is an analog of PGE1 with structural modifications intended to give it a prolonged half-life and greater potency.It is a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost can be used for pain relief, has antianginal effects, and has potential for ischaemic symptoms treatment.
CAS Number
74397-12-9
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
380.52
Molecular Formula
C22H36O5
Notes
Research use only, not for human use.
Receptor
PGE Synthase

Chemical Information

Limaprost

Limaprost is a long-chain fatty acid.

CAS Number74397-12-9
PubChem CID6438378
IUPAC Name(E)-7-[(1R,2R,3R)-3-hydroxy-2-[(E,3S,5S)-3-hydroxy-5-methylnon-1-enyl]-5-oxocyclopentyl]hept-2-enoic acid
Molecular FormulaC22H36O5
Molecular Weight380.5
XLogP4.1
Topological Polar Surface Area94.8
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count13
Heavy Atom Count27
Formal Charge0
Complexity511
SMILES
CCCC[C@H](C)C[C@@H](/C=C/[C@H]1[C@@H](CC(=O)[C@@H]1CCCC/C=C/C(=O)O)O)O
InChI
InChI=1S/C22H36O5/c1-3-4-9-16(2)14-17(23)12-13-19-18(20(24)15-21(19)25)10-7-5-6-8-11-22(26)27/h8,11-13,16-19,21,23,25H,3-7,9-10,14-15H2,1-2H3,(H,26,27)/b11-8+,13-12+/t16-,17+,18+,19+,21+/m0/s1
InChIKey
OJZYRQPMEIEQFC-UAWLTFRCSA-N
Chemical Structure
2D Structure
2D structure of Limaprost
CAS: 74397-12-9
CID: 6438378
Formula: C22H36O5
MW: 380.5
Interactive 3D Structure
Loading 3D structure...
Computed Properties
PropertyValue
Molecular Weight380.5
XLogP34.1
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count5
Rotatable Bond Count13
Exact Mass380.25627424
Monoisotopic Mass380.25627424
Topological Polar Surface Area94.8 Ų
Heavy Atom Count27
Formal Charge0
Complexity511
Isotope Atom Count0
Defined Atom Stereocenter Count5
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count2
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes