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Pyr6

CAT: 1410-M22852-01Size: 5 mgDry Ice: NoHazardous: No
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CAT#:1410-M22852-01Size:5 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
Pyr6 is a selective TRPC3 inhibitor with IC50 of 0.49 uM (Ca2+ influx inhibition in thapsigargin depleted native RBL-2H3 cells) .Pyr6 is an inhibitor of Ca2+ entry, which displays higher potency to inhibit Ca2+ entry mediated by CRAC channel than by TRPC3.Pyr3 is selective inhibitor of TRPC3, inhibited Orai1- and TRPC3-mediated Ca (2+) entry and currents as well as mast cell activation with similar potency.
CAS Number
245747-08-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
418.27
Molecular Formula
C17H9F7N4O
Notes
Research use only, not for human use.
Receptor
TRPC3

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