Estrone

• Description :

  Estrone (E1) is a natural estrogenic hormone. Estrone is the main representative of the endogenous estrogens and is produced by several tissues, especially adipose tissue. Estrone is the result of the process of aromatization of androstenedione that occurs in fat cells[1][2].

• Product Name Alternative :

  E1; Oestrone

• UNSPSC :

  12352005

• Hazard Statement :

  H351, H362

• Target :

  Endogenous Metabolite; Estrogen Receptor/ERR

• Type :

  Natural Products

• Related Pathways :

  Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

• Applications :

  Cancer-programmed cell death

• Field of Research :

  Endocrinology; Cancer

• Assay Protocol :

  https://www.medchemexpress.com/Estrone.html

• Concentration :

  10mM

• Purity :

  99.96

• Solubility :

  DMSO : 25 mg/mL (ultrasonic; warming; heat to 60°C) |H2O : < 0.1 mg/mL (ultrasonic)

• Smiles :

  C[C@]1([C@](CC2)([H])[C@]3([H])CCC4=C(C=CC(O)=C4)[C@@]3([H])CC1)C2=O

• Molecular Formula :

  C18H22O2

• Molecular Weight :

  270.37

• Precautions :

  H351, H362

• References & Citations :

  [1]Caupos E, et al. Photodegradation of estrone enhanced by dissolved organic matter under simulated sunlight. Water Res. 2011;45 (11) :3341-3350.|[2]de Padua Mansur A, et al. Long-term prospective study of the influence of estrone levels on events in postmenopausal women with or at high risk for coronary artery disease. ScientificWorldJournal. 2012;2012:363595.

• Shipping Conditions :

  Room Temperature

• Storage Conditions :

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category :

  Natural Products

• Clinical Information :

  Launched

• Isoform :

  Human Endogenous Metabolite

• CAS Number :

  [53-16-7]