T-025

• Description:

  T-025 (T025, CLK inhibitor T-025) is an orally available, potent inhibitor of Cdc2-like kinases (CLKs) with Kd of 4.8, 0.096, 6.5, and 0.61 nM for CLK1, CLK2, CLK3, and CLK4, also inhibits DYRK1A and DYRK1B with IC50 of 0.074 and 1.5 nM.

• Stability:

  ≥ 2 years

• Purity:

  >98% (HPLC)

• Weight:

  382.431

• Molecular Formula:

  C21H18N8

• Notes:

  Research use only, not for human use.

• Receptor:

  CLK