Products for Research Use Only
RegisterLogin

BIX02188

CAT: 1410-M14136-05Size: 50 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M14136-05Size:50 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
BIX02188 is a potent, selective inhibitor of MEK5 catalytic activity with IC50 of 4.3 nM.
CAS Number
334949-59-6
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
412.4837
Molecular Formula
C25H24N4O2
Notes
Research use only, not for human use.
Receptor
MEK

Chemical Information

(Z)-3-(((3-((dimethylamino)methyl)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxamide

See also: Bix-02188 (annotation moved to).

CAS Number334949-59-6
PubChem CID135398492
IUPAC Name3-[N-[3-[(dimethylamino)methyl]phenyl]-C-phenylcarbonimidoyl]-2-hydroxy-1H-indole-6-carboxamide
Molecular FormulaC25H24N4O2
Molecular Weight412.5
XLogP3.9
Topological Polar Surface Area94.7
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Heavy Atom Count31
Formal Charge0
Complexity645
SMILES
CN(C)CC1=CC(=CC=C1)N=C(C2=CC=CC=C2)C3=C(NC4=C3C=CC(=C4)C(=O)N)O
InChI
InChI=1S/C25H24N4O2/c1-29(2)15-16-7-6-10-19(13-16)27-23(17-8-4-3-5-9-17)22-20-12-11-18(24(26)30)14-21(20)28-25(22)31/h3-14,28,31H,15H2,1-2H3,(H2,26,30)
InChIKey
WGPXKFOFEXJMBD-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of (Z)-3-(((3-((dimethylamino)methyl)phenyl)amino)(phenyl)methylene)-2-oxoindoline-6-carboxamide
CAS: 334949-59-6
CID: 135398492
Formula: C25H24N4O2
MW: 412.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight412.5
XLogP33.9
Hydrogen Bond Donor Count3
Hydrogen Bond Acceptor Count4
Rotatable Bond Count6
Exact Mass412.18992602
Monoisotopic Mass412.18992602
Topological Polar Surface Area94.7 Ų
Heavy Atom Count31
Formal Charge0
Complexity645
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count0
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M11113-01BIX02189
M10368-01BIX02189 (b)

Alternative Products

CatalogName
BA6439-10BIX02188
A10150-25BIX02188 25mg
A10150-1BIX02188 1mg
GTR19163677-01BIX02188 (c)
A10150-10BIX02188 10mg
A10150-100BIX02188 100mg
A10150-50BIX02188 50mg
A10150-5BIX02188 5mg
HY-107622(E/Z) -BIX02188

Popular Products