SAR131675

CAT: 1410-M11844-02Size: 5 mgDry Ice: NoHazardous: No

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CAT#:1410-M11844-02Size:5 mg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Description

AR131675 is highly selective for VEGFR-3 versus 107 receptors, enzymes, ion channels, and 65 kinases.

CAS Number

1433953-83-3

Stability

≥ 2 years

Purity

>98% (HPLC)

Weight

358.39

Molecular Formula

C₁₈H₂₂N₄O₄

Notes

Research use only, not for human use.

Receptor

VEGFR

Chemical Information

(R)-2-amino-1-ethyl-7-(3-hydroxy-4-methoxy-3-methylbut-1-yn-1-yl)-N-methyl-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxamide

CAS Number	1433953-83-3
PubChem CID	71295845
IUPAC Name	2-amino-1-ethyl-7-[(3R)-3-hydroxy-4-methoxy-3-methylbut-1-ynyl]-N-methyl-4-oxo-1,8-naphthyridine-3-carboxamide
Molecular Formula	C18H22N4O4
Molecular Weight	358.4
XLogP	1.1
Topological Polar Surface Area	118
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	6
Heavy Atom Count	26
Formal Charge	0
Complexity	677

SMILES

CCN1C(=C(C(=O)C2=C1N=C(C=C2)C#C[C@](C)(COC)O)C(=O)NC)N

InChI

InChI=1S/C18H22N4O4/c1-5-22-15(19)13(17(24)20-3)14(23)12-7-6-11(21-16(12)22)8-9-18(2,25)10-26-4/h6-7,25H,5,10,19H2,1-4H3,(H,20,24)/t18-/m1/s1

InChIKey

PFMPOBVAYMTUOX-GOSISDBHSA-N

Chemical Structure

2D Structure

CAS: 1433953-83-3

CID: 71295845

Formula: C18H22N4O4

MW: 358.4

Interactive 3D Structure

Loading 3D structure...

Computed Properties

Property	Value
Molecular Weight	358.4
XLogP3	1.1
Hydrogen Bond Donor Count	3
Hydrogen Bond Acceptor Count	7
Rotatable Bond Count	6
Exact Mass	358.16410520
Monoisotopic Mass	358.16410520
Topological Polar Surface Area	118 Å²
Heavy Atom Count	26
Formal Charge	0
Complexity	677
Isotope Atom Count	0
Defined Atom Stereocenter Count	1
Undefined Atom Stereocenter Count	0
Defined Bond Stereocenter Count	0
Undefined Bond Stereocenter Count	0
Covalently-Bonded Unit Count	1
Compound Is Canonicalized	Yes

Catalog	Name
HY-15458-01	SAR131675