Products for Research Use Only
RegisterLogin

ITD-1

CAT: 1410-M10381-04Size: 10 mgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:1410-M10381-04Size:10 mg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Description
ITD-1 is a potent, selective TGF-β inhibitor that induces type II TGFβ receptor (TGFBR2) degradation with IC50 of 0.85 uM.
CAS Number
1099644-42-4
Stability
≥ 2 years
Purity
>98% (HPLC)
Weight
415.524
Molecular Formula
C27H29NO3
Notes
Research use only, not for human use.
Receptor
TGFβ

Chemical Information

Ethyl 2,7,7-trimethyl-5-oxo-4-(4-phenylphenyl)-1,4,6,8-tetrahydroquinoline-3-carboxylate
CAS Number1099644-42-4
PubChem CID44135961
IUPAC Nameethyl 2,7,7-trimethyl-5-oxo-4-(4-phenylphenyl)-1,4,6,8-tetrahydroquinoline-3-carboxylate
Molecular FormulaC27H29NO3
Molecular Weight415.5
XLogP5.3
Topological Polar Surface Area55.4
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Heavy Atom Count31
Formal Charge0
Complexity776
SMILES
CCOC(=O)C1=C(NC2=C(C1C3=CC=C(C=C3)C4=CC=CC=C4)C(=O)CC(C2)(C)C)C
InChI
InChI=1S/C27H29NO3/c1-5-31-26(30)23-17(2)28-21-15-27(3,4)16-22(29)25(21)24(23)20-13-11-19(12-14-20)18-9-7-6-8-10-18/h6-14,24,28H,5,15-16H2,1-4H3
InChIKey
ULFUJLFTRWWLPO-UHFFFAOYSA-N
Chemical Structure
2D Structure
2D structure of Ethyl 2,7,7-trimethyl-5-oxo-4-(4-phenylphenyl)-1,4,6,8-tetrahydroquinoline-3-carboxylate
CAS: 1099644-42-4
CID: 44135961
Formula: C27H29NO3
MW: 415.5
Interactive 3D Structure
Loading 3D structure...
View on PubChemRaw 3D data
Computed Properties
PropertyValue
Molecular Weight415.5
XLogP35.3
Hydrogen Bond Donor Count1
Hydrogen Bond Acceptor Count4
Rotatable Bond Count5
Exact Mass415.21474379
Monoisotopic Mass415.21474379
Topological Polar Surface Area55.4 Ų
Heavy Atom Count31
Formal Charge0
Complexity776
Isotope Atom Count0
Defined Atom Stereocenter Count0
Undefined Atom Stereocenter Count1
Defined Bond Stereocenter Count0
Undefined Bond Stereocenter Count0
Covalently-Bonded Unit Count1
Compound Is CanonicalizedYes

Related Products

CatalogName
M12554-01PD-1-IN-1
M36548-01PU.1-IN-1
M28812-01PHD-1-IN-1
M35554-01TGFβ1-IN-1
M37392-011,1-diethoxypentane
M36426-01TASK-1-IN-1
M26481-01ICAM-1-IN-1
M21114-01Enpp-1-IN-1
M21182-01Vanin-1-IN-1
M37256-01Sirtuin-1 inhibitor 1

Alternative Products

CatalogName
B5858-100ITD 1
T201672-01(+) -ITD-1
HY-12704-01ITD-1
MBS3841372-01(+)-ITD 1

Popular Products