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CRM1 Rabbit mAb

CAT: 0866-RDSA67657Size: 100 µLDry Ice: NoHazardous: No
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CAT#:0866-RDSA67657Size:100 µL
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Mediates the nuclear export of cellular proteins (cargos) bearing a leucine-rich nuclear export signal (NES) and of RNAs. In the nucleus, in association with RANBP3, binds cooperatively to the NES on its target protein and to the GTPase RAN in its active GTP-bound form (Ran-GTP) . Docking of this complex to the nuclear pore complex (NPC) is mediated through binding to nucleoporins.
Description
This is a CRM1 Rabbit mAb Recombinant Antibody from Reddot Biotech. This product is for Research Use Only.
Synonyms
CRM 1; emb; Exp1; Exportin1; XPO 1
Swiss Prot
O14980
Reactivity
Human, Mouse, Rat
Immunogen
A synthesized peptide derived from human CRM1
Clonality
Monoclonal
Conjugation
Unconjugated
Type
Recombinant Antibody
Applications
WB, IHC, ICC/IF, FC
Purification Method
Affinity purification
Assay Type
Antibody
Dilution
WB 1:500-1:2000, IHC 1:50-1:200, ICC/IF 1:50-1:200, FC 1:100
Buffer
Phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage Conditions
Store at -20°C. Avoid freeze / thaw cycles.
Host or Source
Rabbit
Isotype
IgG

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