RANTES (CCL 5)

• Description:

  RANTES is a protein which has been shown to be a chemoattractant for peripheral blood monocytes. It appears to selectively attract T cells of the CD4+/CD45RO+ phenotype in vitro. Recombinant Rat RANTES is a 7.9 kDa protein containing 68 amino acid residues.

• Synonyms:

  Ccl5; Scya5; Rantes

• NCBI Gene ID:

  81780

• UniProt:

  P50231

• Accession Number:

  AAA96499

• Accession Number mRNA:

  U06436

• Chromosomal Location:

  10q26

• Reactivity:

  Rat

• Cross Reactivity:

  Human, Mouse, Rat

• Sequence:

  SPYGSDTTPC CFAYLSLALP RAHVKEYFYT SSKCSNLAVV FVTRRNRQVC ANPEKKWVQE YINYLEMS

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 98% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Assay#1: Determined by its ability to chemoattract rat peritoneal macrophages using a concentration range of 50.0-100.0 ng/ml. Assay#2: Determined by its ability to chemoattract human blood monocytes using a concentration range of 10.0-100.0 ng/ml.

• Length:

  68

• Form:

  Lyophilized

• Molecular Weight:

  7.9 kDa

• Host or Source:

  E. coli