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MCP-2 (CCL8)

CAT: 0209-100-066-L100Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-100-066-L100Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant human MCP-2 is an 8.9 kDa protein containing 76 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Synonyms
CCL8; HC14; MCP2; MCP-2; SCYA8; SCYA10
NCBI Gene ID
6355
UniProt
P80075
Accession Number
NP_005614
Accession Number mRNA
NM_005623
Chromosomal Location
17q11.2
Reactivity
Human
Cross Reactivity
Hamster, Monkey, Mouse, Rat, Human
Sequence
QPDSVSIPIT CCFNVINRKI PIQRLESYTR ITNIQCPKEA VIFKTKRGKE VCADPKERWV RDSMKHLDQI FQNLKP
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
Determined by its ability to chemoattract human peripheral blood monocytes using a concentration range of 10.0-100.0 ng/ml.
Length
76
Form
Lyophilized
Molecular Weight
8.9 kDa
Host or Source
E. coli

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