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IL-7

CAT: 0209-M10-018-L500Size: 500 µgDry Ice: NoHazardous: No
CAT#: M10-018-L500Size: 500 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL-7 is a hematopoietic growth factor which affects primarily early B and T cells. Produced by thymic stromal cells, spleen cells and keratinocytes, IL-7 can also co-stimulate the proliferation of mature T cells in combination with other factors such as ConA and IL-2. Human and murine IL-7 is cross-species reactive. Recombinant murine IL-7 is a 15.0 kDa protein containing 130 amino acid residues.
Synonyms
Il7; Il-7; hlb368; A630026I06Rik
NCBI Gene ID
16196
UniProt
P10168
Accession Number
NP_032397.1
Accession Number mRNA
NM_008371
Chromosomal Location
3 A1; 3 6.6 cM
Reactivity
Mouse
Cross Reactivity
Mouse, Human
Sequence
MECHIKDKEG KAYESVLMIS IDELDKMTGT DSNCPNNEPN FFRKHVCDDT KEAAFLNRAA RKLKQFLKMN ISEEFNVHLL TVSQGTQTLV NCTSKEEKNV KEQKKNDACF LKRLLREIKT CWNKILKGSI
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine 2E8 cells is < 0.2 ng/ml, corresponding to a specific activity of > 5 x 106 units/mg.
Length
130
Form
Lyophilized
Molecular Weight
15 kDa
Host or Source
E. coli

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