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IL-5

CAT: 209-R20-048-L1000Size: 5x 200 µgDry Ice: NoHazardous: No
5x 200 µgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Recombinant rat IL-5 is a 26.0 kDa disulfide-linked homodimeric protein containing two 113 amino acid chains.
Synonyms
Il5; Il-5
NCBI Gene ID
24497
UniProt
Q9R2C9
Accession Number
NP_068606.1
Accession Number mRNA
NM_021834.1
Chromosomal Location
10q22
Reactivity
Rat
Cross Reactivity
Human
Sequence
MEIPMSTVVK ETLIQLSTHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEILFQNL SLIKKYIDGQ KEKCGEERRK TRHFLDYLQE FLGVMSTEWA MEV
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
The ED50 was determined by the dose-dependent stimulation of the proliferation of human TF-1 cells is 2 x 106 units/mg.
Length
113
Form
Lyophilized
Molecular Weight
26 kDa
Host or Source
E. coli

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