RegisterLogin

IL-34

CAT: 0209-100-116-L100Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-100-116-L100Size:100 µg
Selected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
IL-34 is a homodimeric cytokine that is expressed in a range of tissues including spleen, heart, brain, liver, kidney, lung, ovary, thymus, testis, small intestine, prostate and colon. IL-34 is a ligand for colony-stimulating factor-1 receptor (CSF1R), which also binds to CSF-1. It specifically binds CD14+ monocytes, promotes survival and proliferation of human peripheral blood monocytes, and stimulates macrophage colony formation by human bone marrow cells. IL-34, like human CSF-1 stimulates phosphorylation of MAPK1/ERK2 and MAPK3/ERK1. Recombinant human IL-34 is a 52.5 kDa homodimeric glycoprotein consisting of 460 amino acid residues, including a C-terminal His-Tag.
Synonyms
IL34; IL-34; C16orf77
NCBI Gene ID
146433
UniProt
Q6ZMJ4
Accession Number
NP_689669.2
Accession Number mRNA
NM_152456.2
Chromosomal Location
16q22.1
Reactivity
Human
Cross Reactivity
Human
Label
His-tag
Sequence
NEPLEMWPLT QNEECTVTGF LRDKLQYRSR LQYMKHYFPI NYKISVPYEG VFRIANVTRL QRAQVSEREL RYLWVLVSLS ATESVQDVLL EGHPSWKYLQ EVETLLLNVQ QGLTDVEVSP KVESVLSLLN APGPNLKLVR PKALLDNCFR VMELLYCSCC KQSSVLNWQD CEVPSPQSCS PEPSLQYAAT QLYPPPPWSP SSPPHSTGSV RPVRAQGEGL LPHHHHHHHH
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 95% by SDS-PAGE & HPLC analyses
Bioactivity
Measured by its ability to induce secretion of MCP-1 from PBMCs.
Length
460
Form
Lyophilized
Molecular Weight
52.5 kDa
Host or Source
HEK 293 cells

Related Products

CatalogName
100-161SIL-37 (IL-1F7)
100-161-L250IL-37 (IL-1F7)
100-161IL-37 (IL-1F7)
101-M784IL-18 (IL-1F4)
100-161-L100IL-37 (IL-1F7)
100-161-L1000IL-37 (IL-1F7)
100-161-L500IL-37 (IL-1F7)
100-091SIL-36 beta (IL-1F8)
100-092SIL-36 gamma (IL-1F9)
100-160-L500IL-36 alpha (IL-1F6)

Alternative Products

CatalogName
168289IL-34 (IL-34, Interleukin-34)
216710Interleukin 34 (IL-34)
MBS692648-01IL-34
MBS692647-01IL-34
N0370-01IL-34 Antibody
MBS151042-01IL-34 Antibody
MBS153291-01IL-34 Peptide
4779PIL-34 Peptide
HC711236Human IL-34
MBS201062-01Recombinant IL-34

Popular Products