RegisterLogin

GM-CSF

CAT: 209-R20-041-L1000Size: 1000 µgDry Ice: NoHazardous: No
1000 µgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in by endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant rat GM-CSF is a 14.5 kDa globular protein consisting of 128 amino acids residues.
Synonyms
Csf2; Gmcsf; Gm-csf
NCBI Gene ID
116630
UniProt
P48750
Accession Number
NP_446304
Accession Number mRNA
NM_053852.1
Chromosomal Location
10q22
Reactivity
Rat
Cross Reactivity
Mouse, Rat, Human
Sequence
MAPTRSPNPV TRPWKHVDAI KEALSLLNDM RALENEKNED VDIISNEFSI QRPTCVQTRL KLYKQGLRGN LTKLNGALTM IASHYQTNCP PTPETDCEIE VTTFEDFIKN LKGFLFDIPF DCWKPVQK
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
The ED50 was determined by the dose-dependent stimulation of the proliferation of Murine FDC-P1 cells is ≤ 0.01 ng/ml, corresponding to a specific activity of ≥ 1.0 x 108 units/mg.
Length
128
Form
Lyophilized
Molecular Weight
14.5 kDa
Host or Source
E. coli

Related Products

CatalogName
101-M435GM-CSFR alpha
600-069-L1000M-CSF / CSF-1 Protein
600-069-L20M-CSF / CSF-1 Protein
600-069-L100M-CSF / CSF-1 Protein
M60-063-L100M-CSF / CSF-1 Protein (ECD)
M60-063-L1000M-CSF / CSF-1 Protein (ECD)
M10-007-L1000G-CSF
R20-074-L100G-CSF
100-064M-CSF
R20-074SG-CSF

Alternative Products

CatalogName
M41215-01GM-CSF
MBS438320-01GM-CSF
553796GM-CSF
MBS8532990-01GM-CSF
MBS8532826-01GM-CSF
E52Y01501GM-CSF
GWB-6C7681GM-CSF
MBS378146-01GM-CSF
E21-J46GM-CSF
E8ER1909-78GM-CSF

Popular Products