RegisterLogin

GM-CSF

CAT: 209-M10-238-L500Size: 500 µgDry Ice: NoHazardous: No
500 µgSelected
PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Product image 1
1 / 1
Description
GM-CSF is a hematopoietic growth factor that stimulates the development of neutrophils and macrophages and promotes the proliferation and development of early erythroid megakaryocytic and eosinophilic progenitor cells. It is produced in endothelial cells, monocytes, fibroblasts and T-lymphocytes. GM-CSF inhibits neutrophil migration and enhances the functional activity of the mature end-cells. The human and murine molecules are species-specific and exhibit no cross-species reactivity. Recombinant murine GM-CSF is a 14.2 kDa globular protein consisting of 125 amino acid residues.
Synonyms
Granulocyte Macrophage Colony-Stimulating Factor, CSF-2, MGI-1GM, pluripoietin-alpha
NCBI Gene ID
12981
UniProt
P01587
Accession Number
NP_034099.2
Accession Number mRNA
NM_009969.4
Chromosomal Location
11 B1.3; 11 29.5 cM
Reactivity
Mouse
Cross Reactivity
Mouse
Sequence
MAPTRSPITV TRPWKHVEAI KEALNLLDDM PVTLNEEVEV VSNEFSFKKL TCVQTRLKIF EQGLRGNFTK LKGALNMTAS YYQTYCPPTP ETDCETQVTT YADFIDSLKT FLTDIPFECK KPVQK
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
> 98% by SDS-PAGE & HPLC analyses
Bioactivity
The ED50 as determined by the dose-dependent stimulation of the proliferation of murine FDC-P1 cells is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Length
125
Form
Lyophilized
Molecular Weight
14.2 kDa
Host or Source
E. coli

Related Products

CatalogName
101-M435GM-CSFR alpha
600-069-L1000M-CSF / CSF-1 Protein
600-069-L20M-CSF / CSF-1 Protein
600-069-L100M-CSF / CSF-1 Protein
M60-063-L100M-CSF / CSF-1 Protein (ECD)
M60-063-L1000M-CSF / CSF-1 Protein (ECD)
R20-050-L1000M-CSF
M10-007-L1000G-CSF
R20-074-L100G-CSF
100-064M-CSF

Alternative Products

CatalogName
553796GM-CSF
M41215-01GM-CSF
MBS438320-01GM-CSF
MBS378146-01GM-CSF
E52Y01501GM-CSF
GWB-6C7681GM-CSF
MBS8532990-01GM-CSF
MBS8532826-01GM-CSF
E21-J46GM-CSF
E8ER1909-78GM-CSF

Popular Products