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G-CSF (Animal Free)

CAT: 0209-M10-007-L250-AFSize: 250 µgDry Ice: NoHazardous: No
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CAT#:0209-M10-007-L250-AFSize:250 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
G-CSF is a hematopoietic growth factor that stimulates the development of committed progenitor cells to neutrophils and enhances the functional activities of the mature end-cell. It is produced in response to specific stimulation by a variety of cells, including macrophages, fibroblasts, endothelial cells and bone marrow stroma. G-CSF is being used clinically to facilitate hematopoietic recovery after bone marrow transplantation. Human and murine G-CSF is cross-species reactive. Recombinant Murine G-CSF is a 19.0 kDa protein consisting of 179 amino acid residues.
Synonyms
Csf3; Csfg; G-CSF; MGI-IG
NCBI Gene ID
12985
UniProt
P09920
Accession Number
NP_034101.1
Accession Number mRNA
NM_009971
Chromosomal Location
11 D; 11 57.0 cM
Reactivity
Mouse
Cross Reactivity
Mouse, Rat
Sequence
MVPLVTVSAL PPSLPLPRSF LLKSLEQVRK IQASGSVLLE QLCATYKLCH PEELVLLGHS LGIPKASLSG CSSQALQQTQ CLSQLHSGLC LYQGLLQALS GISPALAPTL DLLQLDVANF ATTIWQQMEN LGVAPTVQPT QSAMPAFTSA FQRRAGGVLA ISYLQGFLET ARLALHHLA
Endotoxin
< 0.01 ng/µg of protein (< 0.1 EU/µg)
Purity
≥ 98% by SDS-PAGE gel and HPLC analyses.
Bioactivity
Determined by its ability to stimulate the proliferation of mouse NFS-60 cells. The expected ED50 is ≤ 0.05 ng/ml, corresponding to a specific activity of ≥ 2 x 107 units/mg.
Length
179
Form
Lyophilized
Molecular Weight
19.0 kDa
Host or Source
E. coli

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