FGF-9

• Description:

  FGF-9 is a heparin binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development and postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-9 targets glial cells, astrocytes cells and other cells that express the FGFR 1c, 2c, 3b, 3c, and 4. Recombinant human FGF-9 is a 23.2 kDa protein consisting of 206 amino acid residues.

• Synonyms:

  FGF9; GAF; SYNS3; HBFG-9

• NCBI Gene ID:

  2254

• UniProt:

  P31371

• Accession Number:

  NP_002001.1

• Accession Number mRNA:

  NM_002010

• Chromosomal Location:

  13q11-q12

• Reactivity:

  Human

• Cross Reactivity:

  Human, Mouse

• Sequence:

  PLGEVGNYFG VQDAVPFGNV PVLPVDSPVL LSDHLGQSEA GGLPRGPAVT DLDHLKGILR RRQLYCRTGF HLEIFPNGTI QGTRKDHSRF GILEFISIAV GLVSIRGVDS GLYLGMNEKG ELYGSEKLTQ ECVFREQFEE NWYNTYSSNL YKHVDTGRRY YVALNKDGTP REGTRTKRHQ KFTHFLPRPV DPDKVPELYK DILSQS

• Endotoxin:

  < 0.1 ng/µg of protein (< 1EU/µg)

• Purity:

  > 95% by SDS-PAGE & HPLC analyses

• Bioactivity:

  Determined by its ability to stimulate the proliferation of mouse balb/c 3T3 cells using a concentration range of 1.0-5.0 ng/ml.

• Length:

  206

• Form:

  Lyophilized

• Molecular Weight:

  23.2 kDa

• Host or Source:

  E. coli