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FGF-10

CAT: 0209-M10-043-L100Size: 100 µgDry Ice: NoHazardous: No
CAT#:0209-M10-043-L100Size:100 µg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Description
FGF-10 is a heparin-binding growth factor that belongs to the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-10 is most related to FGF-7/KGF, and is expressed during the development and, preferentially, in adult lungs. It signals through FGFR 2b. Recombinant Murine FGF-10 is a 17.0 kDa protein consisting of 148 amino acid residues.
Synonyms
Fibroblast Growth Factor‐10, FGFA, Keratinocyte Growth Factor‐2
NCBI Gene ID
14165
UniProt
O35565
Accession Number
NP_032028.1
Accession Number mRNA
NM_008002.4
Reactivity
Mouse
Cross Reactivity
Mouse
Sequence
SSAGRHVRSY NHLQGDVRWR RLFSFTKYFL TIEKNGKVSG TKNEDCPYSV LEITSVEIGV VAVKAINSNY YLAMNKKGKL YGSKEFNNDC KLKERIEENG YNTYASFNWQ HNGRQMYVAL NGKGAPRRGQ KTRRKNTSAH FLPMTIQT
Assay Protocol
Centrifuge the vial prior to opening. Reconstitute in sterile water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Endotoxin
< 0.1 ng/µg of protein (< 1EU/µg)
Purity
≥ 95% by SDS-PAGE gel and HPLC analyses
Bioactivity
Determined by dose-dependent ability to reduce tetrazolium salt, WST-8, by dehydrogenase activities of BaF3 cells expressing FGF receptors using Cell Counting Kit-8 (CCK-8) .
Length
148
Form
Lyophilized
Molecular Weight
17.0 kDa
Storage Conditions
The lyophilized protein is stable at room temperature for 3 weeks should be stored desiccated below -18°C. Reconstituted working aliquots are stable for 1 week at 2°C to 8°C and for 3 months at -20°C to -80°C.
Host or Source
E. coli

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