Recombinant MBD2 Monoclonal Antibody

• Background:

  MBD2, also named as DMTase, binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. MBD2 binds hemi-methylated DNA as well. It recruits histone deacetylases and DNA methyltransferases. MBD2 acts as transcriptional repressor and plays a role in gene silencing.

• Abbreviation:

  MBD2

• UniProt:

  Q9UBB5

• Host:

  Rabbit

• Reactivity:

  Human; Rat; Mouse

• Immunogen:

  Recombinant human MBD2 fragment

• Target:

  MBD; NY-CO; MBD2; DMTase; NY-CO-41; DKFZp586O0821

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A621

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC; IF

• Field of Research:

  Epigenetics and Nuclear Signaling

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:1000; IHC 1:200-1:1000; IF 1:50

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  43 kDa

• Observed Molecular Weight:

  43, 29 kDa

• Isotype:

  IgG, κ