Recombinant ING5 Monoclonal Antibody

• Background:

  Inhibitor of growth protein 5 is a protein that in humans is encoded by the ING5 gene. The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in TP53-dependent regulatory pathway.

• Abbreviation:

  ING5

• UniProt:

  Q8WYH8

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Recombinant human ING5 fragment

• Target:

  ING; p28ING; ING5; p28ING5

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A265

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Epigenetics and Nuclear Signaling

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000; IHC 1:50-1:100

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  32 kDa

• Observed Molecular Weight:

  32 kDa

• Isotype:

  IgG, κ