Recombinant Caspase-7 Monoclonal Antibody

• Background:

  Involved in the activation cascade of caspases responsible for apoptosis execution. Cleaves and activates sterol regulatory element binding proteins (SREBPs) . Proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Overexpression promotes programmed cell death.

• Abbreviation:

  Caspase-7

• UniProt:

  P55210

• Host:

  Rabbit

• Reactivity:

  Human; Mouse

• Immunogen:

  Recombinant human Caspase-7 fragment

• Target:

  MCH; LICE; Caspase-7 subunit p; ICE-like apoptotic protease; ICE-LAP; ICE LAP; CMH; CASP7; CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3; caspase-7; Apoptotic protease MCH3; Apoptotic protease Mch-3; Caspase 7; Caspase 7 apoptosis related cysteine peptidase; Caspase7; Caspase-7 subunit p11; CMH 1; CMH1; ICE LAP3; ICE-like apoptotic protease 3

• Clonality:

  Monoclonal, Recombinant

• Clone:

  A151

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cell Biology; Cancer; Metabolism

• Purification:

  Protein A purified

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:2000; IHC 1:200-1:1000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  34 kDa

• Observed Molecular Weight:

  18, 32, 35 kDa

• Isotype:

  IgG, κ