Recombinant ATG5 Monoclonal Antibody

• Background:

  The protein encoded by this gene, in combination with autophagy protein 12, functions as an E1-like activating enzyme in a ubiquitin-like conjugating system. The encoded protein is involved in several cellular processes, including autophagic vesicle formation, mitochondrial quality control after oxidative damage, negative regulation of the innate antiviral immune response, lymphocyte development and proliferation, MHC II antigen presentation, adipocyte differentiation, and apoptosis. Several transcript variants encoding different protein isoforms have been found for this gene.

• Abbreviation:

  ATG5

• UniProt:

  Q9H1Y0

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human ATG5 protein

• Target:

  ATG; APG; hAPG; Autophagy protein; ATG5; APG5; APG5-LIKE; APG5L; ASP; hAPG5; Apoptosis-specific protein; Autophagy protein 5; APG 5; APG 5L; APG5 autophagy 5 like; APG5 like; Apoptosis specific protein; ATG 5; ATG5 autophagy related 5 homolog; Autophagy related 5; Homolog of S Cerevisiae autophagy 5; OTTHUMP00000040507

• Clonality:

  Monoclonal, Recombinant

• Clone:

  8B5

• Conjugation:

  Unconjugated

• Applications:

  WB; IHC

• Field of Research:

  Cell Biology; Cardiovascular; Cancer; Metabolism

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  IHC 1:200-1:1000; WB 1:2000-1:10000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  33 kDa

• Observed Molecular Weight:

  55 kDa

• Isotype:

  IgG, κ