Recombinant EZH2 Monoclonal Antibody

• Background:

  EZH2 (enhancer of zeste 2 polycomb repressive complex 2 subunit) Homo sapiens This gene encodes a member of the Polycomb-group (PcG) family. PcG family members form multimeric protein complexes, which are involved in maintaining the transcriptional repressive state of genes over successive cell generations. This protein associates with the embryonic ectoderm development protein, the VAV1 oncoprotein, and the X-linked nuclear protein. This protein may play a role in the hematopoietic and central nervous systems. Multiple alternatively splcied transcript variants encoding distinct isoforms have been identified for this gene.

• Abbreviation:

  EZH2

• UniProt:

  Q15910

• Host:

  Rabbit

• Reactivity:

  Human; Mouse; Rat

• Immunogen:

  Recombinant Human EZH2 protein

• Target:

  KMT; KMT6 / EZH; EZH; ENX; ENX-1; ENX1; EZH1; EZH2b; KMT6; KMT6A; WVS; WVS2; EZH2; KMT6 / EZH2

• Clonality:

  Monoclonal, Recombinant

• Clone:

  12G12

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Epigenetics and Nuclear Signaling; Cancer

• Purification:

  Protein A

• Concentration:

  0.2 mg/mL

• Dilution:

  WB 1:2000-1:10000

• Buffer:

  PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.

• Calculated Molecular Weight:

  85 kDa

• Observed Molecular Weight:

  85 kDa

• Isotype:

  IgG, κ