Cystatin 7/CST7 Monoclonal Antibody

• Background:

  The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. This gene encodes a glycosylated cysteine protease inhibitor with a putative role in immune regulation through inhibition of a unique target in the hematopoietic system. Expression of the protein has been observed in various human cancer cell lines established from malignant tumors.

• Abbreviation:

  CST7

• UniProt:

  O76096

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Recombinant Human CST7 protein

• Target:

  CST; Cystatin; CST7; CMAP; Cystatin-7; Cystatin-F; Cystatin-Like Metastasis-Associated Protein; Leukocystatin

• Clonality:

  Monoclonal

• Clone:

  6C6

• Conjugation:

  Unconjugated

• Applications:

  WB

• Field of Research:

  Cardiovascular; Cell Biology

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  WB 1:500-1:1000

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  21 kDa

• Observed Molecular Weight:

  27 kDa

• Isotype:

  IgG1