Cystatin A/CSTA Monoclonal Antibody

• Background:

  The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins, and kininogens. This gene encodes a stefin that functions as a cysteine protease inhibitor, forming tight complexes with papain and the cathepsins B, H, and L. The protein is one of the precursor proteins of cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Stefins have been proposed as prognostic and diagnostic tools for cancer.

• Abbreviation:

  CSTA

• UniProt:

  P01040

• Host:

  Mouse

• Reactivity:

  Human

• Immunogen:

  Recombinant Human Cystatin A/CSTA protein

• Target:

  PSS; STF; CSTA; AREI; PSS4; STF1; STFA; Cystatin-A; Cystatin-AS; Stefin-A; Stefin A

• Clonality:

  Monoclonal

• Clone:

  2C8

• Conjugation:

  Unconjugated

• Applications:

  IHC-P

• Field of Research:

  Cell Biology; Signal Transduction; Cancer

• Purification:

  Protein A

• Concentration:

  1 mg/mL

• Dilution:

  IHC-P 1:50-1:200

• Buffer:

  0.2 μm filtered solution in PBS

• Shipping Conditions:

  Ice bag

• Storage Conditions:

  This antibody can be stored at 2°C-8°C for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20°C to -80°C. Preservative-Free. Avoid repeated freeze-thaw cycles.

• Isotype:

  IgG1