Enterokinase Recombinant Protein

• Background:

  Proteases (also called Proteolytic Enzymes, Peptidases, or Proteinases) are enzymes that hydrolyze the amide bonds within proteins or peptides. Most proteases act in a specific manner, hydrolyzing bonds at or adjacent to specific residues or a specific sequence of residues contained within the substrate protein or peptide. Proteases play an important role in most diseases and biological processes including prenatal and postnatal development, reproduction, signal transduction, the immune response, various autoimmune and degenerative diseases, and cancer. They are also an important research tool, frequently used in the analysis and production of proteins. Enterokinase sequentially cleaves carboxyl side of D-D-D-D-K. Human Enterokinase is expressed as a linear 1019 amino acid polypeptide precursor glycoprotein. Proteolytic processing of this precursor generates the biologically active form of Enterokinase, which consists of two polypeptide chains (heavy chain and light chain) held together by a single disulfide bond, resulting in formation of a biologically active heterodimer. The heavy chain consists of 784 amino acid residues, and the light consists of 235 amino acid residues.

• NCBI Gene ID:

  5651

• Swiss Prot:

  P98073

• Accession Number:

  NP_002763.2

• Type:

  Recombinant Proteins

• Source:

  CHO cells

• Field of Research:

  Cell Cycle

• Purity:

  Greater than 90% by SDS-PAGE gel and HPLC analyses.

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized Enterokinase recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Enterokinase stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Enterokinase recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Transmembrane protease, serine 15

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  ENTK, PRSS7, ENTK, Enteropeptidase, Enterokinase

• Species:

  Human

• Protein ID:

  223942069

• Physical Properties:

  Lyophilized