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LIGHT Recombinant Protein

CAT: 0223-40-452-01Size: 0.005 mgDry Ice: NoHazardous: No
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CAT#:0223-40-452-01Size:0.005 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβ R, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFkB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues.
NCBI Gene ID
50930
Swiss Prot
Q9QYH9
Accession Number
NP_062291.1
Type
Recombinant Proteins
Source
E. coli
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized LIGHT recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted LIGHT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing LIGHT recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Tumor necrosis factor (ligand) superfamily, member 14
NCBI Organism
Mus musculus
Other Product Names
LTg, HVEML, LIGHT, Ly113, HVEM-L, Light, Tumor necrosis factor ligand superfamily member 14
Species
Murine
Protein ID
9507195
Physical Properties
Lyophilized

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