LIGHT Recombinant Protein

• Background:

  LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTβ R, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NFkB, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Recombinant murine LIGHT is a 20.1 kDa protein containing 183 amino acid residues.

• NCBI Gene ID:

  50930

• Swiss Prot:

  Q9QYH9

• Accession Number:

  NP_062291.1

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized LIGHT recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted LIGHT is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing LIGHT recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Tumor necrosis factor (ligand) superfamily, member 14

• NCBI Organism:

  Mus musculus

• Other Product Names:

  LTg, HVEML, LIGHT, Ly113, HVEM-L, Light, Tumor necrosis factor ligand superfamily member 14

• Species:

  Murine

• Protein ID:

  9507195

• Physical Properties:

  Lyophilized