LIGHT Antibody

• Background:

  LIGHT is a type II membrane protein belonging to the TNF family of membrane-anchored ligands. It is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes and monocytes. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells.

• NCBI Gene ID:

  8740

• Swiss Prot:

  O43557

• Accession Number:

  O43557

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Produced from sera of rabbits pre-immunized with highly pure (>98%) recombinant hLIGHT (human LIGHT) .

• Clonality:

  Polyclonal

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies, Antibody Pairs

• Field of Research:

  Infectious Disease, Apoptosis, Chemokines & Cytokines

• Purification:

  Anti-hLIGHT specific antibody was purified by affinity chromatography employing immobilized hLIGHT matrix.

• Concentration:

  Batch dependent

• Modification:

  None

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  LIGHT antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.

• Symbol:

  TNFSF14

• NCBI Official Name:

  Tumor necrosis factor (ligand) superfamily, member 14

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  LTg, TR2, CD258, HVEML, LIGHT, UNQ391/PRO726, Tumor necrosis factor ligand superfamily member 14, Herpes virus entry mediator ligand, HVEM-L

• Tested Applications:

  ELISA, WB

• Protein ID:

  313104028

• Physical Properties:

  Lyophilized