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Galectin-3 Recombinant Protein

CAT: 0223-40-329-01Size: 0.01 mgDry Ice: NoHazardous: No
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CAT#:0223-40-329-01Size:0.01 mg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Lectins, of either plant or animal origin, are carbohydrate binding proteins that interact with glycoprotein and glycolipids on the surface of animal cells. The Galectins are lectins that recognize and interact with beta-galactoside moieties. Galectin-3 regulates a number of biological processes, including embryogenesis, inflammatory responses, cell progression and metastasis. Galectin-3 is normally expressed in epithelia of a variety of tissues, including colon and endometrium, and in various inflammatory cells, including macrophages. Galectin-3 can function intracellularly, in controlling cell cycle and preventing T-cell apoptosis, and also extracellularly, in activating various cells, including monocytes/macrophages, mast cells, neutrophils, and lymphocytes. Expression of Galectin-3 is affected by neoplastic transformation, being up-regulated in certain types of lymphomas, and in thyroid and hepatic carcinomas. Conversely, it is down-regulated in other cancers, such as colon, breast, ovarian, and uterine. Recombinant human Galectin-3 is a globular 26.0kDa protein containing 250 amino acid residues, but no disulfide bonds.
NCBI Gene ID
3958
Swiss Prot
P17931
Accession Number
NP_002297.2
Type
Recombinant Proteins
Source
E. coli
Field of Research
Cell Cycle, Neuroscience, Other
Shipping Conditions
Room Temp
Storage Conditions
The lyophilized Galectin-3 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Galectin-3 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Galectin-3 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
NCBI Official Name
Lectin, galactoside-binding, soluble, 3
NCBI Organism
Homo sapiens
Other Product Names
L31, GAL3, MAC2, CBP35, GALBP, GALIG, LGALS2, Galectin-3, 35 kDa lectin, Gal-3
Species
Human
Protein ID
115430223
Physical Properties
Lyophilized

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