Galectin-9 Recombinant Protein

• Background:

  Galectin-9 (LGALS9) is also known as tumor antigen HOM-HD-21 and ecalectin. Galectins are a family of proteins defined by their binding specificity for beta-galactoside sugars, such as N-acetyllactosamine (Galbeta1-3GlcNAc or Galbeta1-4GlcNAc), which can be bound to proteins by either N-linked or O-linked glycosylation. As for Galectin-9, it has high affinity for the Forssman pentasaccharide, and it is also the ligand for HAVCR2/TIM3. Forthermore, Galectin-9 stimulates bactericidal activity in infected macrophages by causing macrophage activation and IL1B secretion which restricts intracellular bacterial growth.

• NCBI Gene ID:

  3965

• Swiss Prot:

  BAA31542

• Accession Number:

  BAA31542

• Tag:

  His Tag

• Type:

  Recombinant Proteins

• Source:

  HEK293 cells

• Field of Research:

  Immunology

• Buffer:

  20 mM MOPS, 50 mM NaCl, 1 mM EDTA, 2 mM DTT, pH7.4

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.

• Calculated Molecular Weight:

  36.6 kDa

• Applications Notes:

  This recombinant protein can be used for WB. For research use only.

• NCBI Official Name:

  Galectin-9 isoform short

• NCBI Organism:

  Homo sapiens

• Background Reference 01:

  Tuereci O., et al., 1997, J. Biol. Chem. 272:6416-6422.

• Background Reference 02:

  Dai S.Y., et al.,2005, J. Immunol. 175:2974-2981.

• Other Product Names:

  Galectin-9, LGALS9, Ecalectin

• Tested Applications:

  WB

• Species:

  Human

• Physical Properties:

  Lyophilized

• CAS Number:

  9000-83-3