Soluble TRAIL Receptor-1 Recombinant Protein

• Background:

  TRAIL Receptor-1/DR4 and TRAIL Receptor-2/DR5 belong to the TNFR superfamily of transmembrane proteins and contain a cytoplasmic "death domain, " which can activate the cell's apoptotic machinery. These receptors are activated by binding to either membrane anchored or soluble TRAIL/Apo2L. Recombinant human soluble TRAIL Receptor-1/DR4 is a 22.7 kDa protein (215 amino acid residues) consisting of the TNFR homologous, cysteine rich portion of the extracellular domain.

• NCBI Gene ID:

  8797

• Swiss Prot:

  O00220

• Accession Number:

  NP_003835.3

• Type:

  Recombinant Proteins

• Source:

  E. coli

• Field of Research:

  Apoptosis, Cancer, Homeostasis, Immunology, Signal Transduction

• Shipping Conditions:

  Room Temp

• Storage Conditions:

  The lyophilized Soluble TRAIL Receptor-1 recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted Soluble TRAIL Receptor-1 is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing Soluble TRAIL Receptor-1 recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

• NCBI Official Name:

  Tumor necrosis factor receptor superfamily, member 10a

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  DR4, APO2, CD261, TRAILR1, TRAILR-1, DR4, Tumor necrosis factor receptor superfamily member 10A, Death receptor 4, TRAIL receptor 1

• Species:

  Human

• Protein ID:

  259906438

• Physical Properties:

  Lyophilized