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Adipolean Antibody

CAT: 0223-XP-5101Size: 0.1 mgDry Ice: NoHazardous: No
CAT#: XP-5101Size: 0.1 mg
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PRICE
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Adipose cells produce and secrete numerous physiologically important proteins, such as Lipoprotein Lipase, Leptin, and Adipocyte Complement Related protein of 30 kDa, also known as Acrp30 or Adiponectin. Adiponectin is a circulating protein that is secreted exclusively by differentiated adipocytes. During adipocyte differentiation, Adiponectin mRNA is induced >100 fold. Adiponectin improves the ability of insulin to suppress glucose production, at sub physiological levels, thereby linking adipose tissue to whole body glucose regulation. Adiponectin function appears to be regulated by phosphatidylinositol 3 kinase (PI3K) since Adiponectin secretion is blocked by pharmacologic inhibitors of this kinase. Adiponectin mRNA is significantly reduced in adipose tissue of obese patients with Type 2 diabetes. The structural similarity of Adiponectin to TNF alpha suggests that Adiponectin may play a role in pathogenesis of insulin resistance in Type 2 diabetes. Adiponectin is implicated as a regulator of whole body energy homeostasis.
NCBI Gene ID
9370
Swiss Prot
Q15848
Accession Number
Q15848
Host
Goat
Reactivity
Human
Immunogen
Produced from sera of goats pre-immunized with highly pure (>98%) recombinant hgAcrp30/Adipolean (human gAcrp30/Adipolean) .
Clonality
Polyclonal
Conjugation
Unconjugated
Type
Primary Antibodies, Antibody Pairs
Field of Research
Obesity
Concentration
Batch dependent
Modification
None
Shipping Conditions
Room Temp
Storage Conditions
Adipolean antibody is stable for at least 2 years from date of receipt at -20˚ C. The reconstituted antibody is stable for at least two weeks at 2-8˚ C. Frozen aliquots are stable for at least 6 months when stored at -20˚ C. Avoid repeated freeze-thaw cycles.
Symbol
ADIPOQ
NCBI Official Name
Adiponectin, C1Q and collagen domain containing
NCBI Organism
Homo sapiens
Other Product Names
ACDC, ADPN, APM1, APM-1, GBP28, ACRP30, ADIPQTL1, ACDC, Adiponectin, 30 kDa adipocyte complement-related protein
Tested Applications
ELISA, WB
Protein ID
2493789
Physical Properties
Lyophilized

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