CD95 Antibody [DX3]

• Background:

  CD95, also known as Fas and APO-1, is a 45 kDa type I transmembrane glycoprotein and a member of the tumor necrosis factor receptor superfamily. It is expressed by activated lymphocytes, monocytes, neutrophils, fibroblasts, and cell lines. Fas ligand binding to CD95 induces apoptosis in activated mature lymphocytes thereby playing a role in maintaining peripheral tolerance.

• NCBI Gene ID:

  355

• Swiss Prot:

  P25445

• Accession Number:

  P25445

• Host:

  Mouse

• Reactivity:

  Human, Rat

• Immunogen:

  Human CD95 transfected L cells

• Clonality:

  Monoclonal

• Clone:

  [DX3]

• Conjugation:

  Unconjugated

• Type:

  Primary Antibodies

• Field of Research:

  Cancer, Cell Cycle, Immunology, Signal Transduction

• Concentration:

  0.1 mg/mL

• Buffer:

  Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG2a

• Specificity:

  CD95

• Applications Notes:

  CD95 Antibody [DX3] for use in flow cytometry, ELISA, and immunohistochemistry assays.

• Symbol:

  FAS

• NCBI Official Name:

  Tumor necrosis factor receptor superfamily member 6

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  APO-1, Fas, TNFRSF6

• Tested Applications:

  Flow

• Physical Properties:

  Liquid