CD35 Antibody [E11] (FITC)

• Background:

  The CD35 antigen is composed of four different allotypes having different molecular weights [A (or F) - 160 kDa, B (or S) - 190 kDa, C - 220 kDa, and D - 250 kDa]. It is the receptor for C3b and is found on B cells, a subset of T cells, monocytes, neutrophils, follicular dendritic cells, erythrocytes, and kidney glomelular podocytes. CD35 mediates neutrophil and monocyte phagocytosis of particles coated with C3b and/or C4b. This interaction also enhances phagocytosis mediated by the Fc receptors.

• NCBI Gene ID:

  1378

• Swiss Prot:

  P17927

• Accession Number:

  P17927

• Host:

  Mouse

• Reactivity:

  Human, Rhesus Monkey, Cynomolgus Monkey, Chimpanzee, Baboon

• Immunogen:

  Acute monocytic leukemia cells and normal blood monocytes

• Clonality:

  Monoclonal

• Clone:

  [E11]

• Conjugation:

  FITC

• Type:

  Primary Antibodies

• Field of Research:

  Immunology, Stem Cell

• Concentration:

  Batch dependent

• Buffer:

  Supplied in PBS/NaN3

• Modification:

  None

• Shipping Conditions:

  Blue Ice

• Storage Conditions:

  Store vial at 2-8˚ C

• Fragment:

  IgG1

• Specificity:

  CD35

• Applications Notes:

  CD35 Antibody [E11] for use in flow cytometry, immunohistochemistry, and western blotting assays.

• Symbol:

  CR1

• NCBI Official Name:

  Complement component (3b/4b) receptor 1 (Knops blood group)

• NCBI Organism:

  Homo sapiens

• Other Product Names:

  CR1, complement receptor type 1, C3bR, C4bR, immune adherence receptor

• Tested Applications:

  Flow

• Physical Properties:

  Liquid