CD35 Antibody [E11]

• Background :

  The CD35 antigen is composed of four different allotypes having different molecular weights [A (or F) - 160 kDa, B (or S) - 190 kDa, C - 220 kDa, and D - 250 kDa]. It is the receptor for C3b and is found on B cells, a subset of T cells, monocytes, neutrophils, follicular dendritic cells, erythrocytes, and kidney glomelular podocytes. CD35 mediates neutrophil and monocyte phagocytosis of particles coated with C3b and/or C4b. This interaction also enhances phagocytosis mediated by the Fc receptors.

• NCBI Gene ID :

  1378

• Swiss Prot :

  P17927

• Accession Number :

  P17927

• Host :

  Mouse

• Reactivity :

  Human, Rhesus Monkey, Cynomolgus Monkey, Chimpanzee, Baboon

• Immunogen :

  Acute monocytic leukemia cells and normal blood monocytes

• Clonality :

  Monoclonal

• Clone :

  [E11]

• Conjugation :

  Unconjugated

• Type :

  Primary Antibodies

• Field of Research :

  Immunology, Stem Cell

• Concentration :

  0.1 mg/mL

• Buffer :

  Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

• Modification :

  None

• Shipping Conditions :

  Blue Ice

• Storage Conditions :

  Store vial at 2-8˚ C

• Fragment :

  IgG1

• Specificity :

  CD35

• Applications Notes :

  CD35 Antibody [E11] for use in flow cytometry, immunohistochemistry, western blotting, ELISA, and immunoprecipitation assays.

• Symbol :

  CR1

• NCBI Official Name :

  Complement component (3b/4b) receptor 1 (Knops blood group)

• NCBI Organism :

  Homo sapiens

• Other Product Names :

  CR1, complement receptor type 1, C3bR, C4bR, immune adherence receptor

• Tested Applications :

  Flow

• Physical Properties :

  Liquid